1
Q
What are the medications for cellulitis
A
Cephalexin & clindamycin
2
Q
Class of Cephalexin
A
Beta lactam (1st gen cephalosporin)
3
Q
Class of Clindamycin
A
Lincosamide protein synthesis inhibitor
4
Q
MOA of Cephalexin
A
Inhibit bacteria cell wall synthesis
5
Q
MOA of Clindamycin
A
Protein synthesis inhibitors
6
Q
Why is Cephalexin used
A
Broad spectrum (good coverage of gram +ve & -ve bacteria)
7
Q
Why is clindamycin used
A
Broad spectrum (gram +ve, -ve, anaerobic when less toxic alternatives are not effective)
Good for MRSA
8
Q
AE of Cephalexin
A
Rash, diarrhoea, thrombophlebitis
9
Q
AE of clindamycin
A
Nausea, diarrhoea, constipation, headache, vomiting, anaphylaxis, superinfection, myopathy, pseudomembranous colitis
Pharmaco
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