Cervical Ca

Question 1

What’s the risk factors of cancer cervix?

Answer 1

1. Sexual behavior:
   - Early initiation of the sexual intercourse
   - History of genital HPV infection or other STD; herpes and HIV
   -Multiple sexual partners
2. Smoking.
3. Low social economic conditions.
4. Long term use OCP.
5. Poor nutritional status. 

Question 2

What’s the etiology for the cervical cancer?

Answer 2

HPV

Question 3

What’s the type of HPV

Answer 3

بالمحاظره جدول

Question 4

Cin

Answer 4

Pre invasive cervical legion that may progress to invasive carcinoma

Question 5

Carcinoma in situ

Answer 5

Microscopic picture ( surface epithelium of the cervix show malignant , a change involves full thickness of the epithelium, but doesn’t invade the basement membrane ).

Question 6

The signifcant features of CIN lesion are? 4

Answer 6

• Cellular immaturity
  -Nuclear abnormalities
  -Cellular disorganization
• Increase mitotic figures

Question 7

What’s the classification of CIN?

Answer 7

1. CIN1. ( mild dysplasia. Lower 1/3. )
2. CIN 2 ( moderate dysplasia lower 2/3)
3. CIN. 3 ( severe dysplasia carcinoma in situ.)

Question 8

How u Can diagnose CIN

Answer 8

Screening test.

Question 9

Bethesda system results 5.

Answer 9

جدول سلايد ١٠

Question 10

What’s the test you will do for the patient with a low-grade or she need to follow up

Answer 10

Colposcopy

Question 11

When you will do the colposcopy?

Answer 11

1. Abnormal pap test
2. Has symptoms and signs.

Question 12

What’s the complication of the radical hysterectomy acute

Answer 12

1. Blood loss.
2. Uretrovagina fistula.
3. Vesicovagina fistula.
4. Small bowel obstruction.
5. Pulmonary embolus.

Question 13

What’s the complication of the radical hysterectomy subacute

Answer 13

Bladder dysfunction

Question 14

What’s the complication of the radical hysterectomy chronic

Answer 14

1. Bladder hypotonia or atony
2. Ureteral strictures

Question 15

What’s the result of radical hysterectomy

Answer 15

Survival 85%

Question 16

When we gonna give post operative radiotherapy

Answer 16

1. Metastasis to the pelvic lymph node.
2. Positive surgical margin.

Question 17

Radiotherapy in cervical cancer

Answer 17

Extremely sensitive

Question 18

When we give radiotherapy

Answer 18

For all patient
All the stages of the invasive cervical cancer

Question 19

What’s the type of radiotherapy?

Answer 19

1. External pelvic irradiation.( Teletherapy ): the use of various doses delivered to diferent proportions the patient pelvis ( 4000-6000 cGy)
2. Intracavitary therapy ( brachytherapy ) : provided by inserting a hollow applicator into
   the uterine cavity.
   The sum of radiation doses required for central tumor control is (2000 – 3000 cGy )

Question 20

What’s the complication of the radiotherapy

Answer 20

1. Perforation of the uterus. ( due to insertion of uterine tendon, especially elderly
2. Fever
3. Acute: due to effect of ionizing radiation on epithelium ( intestine, and bladder ) leading to:
   diarrhea, abdominal cramps, nausea( enteritis)
   Frequent urination, hematuria ( cystitis)
   small bowel complication ( small bowel fistula)
   Urinary tract (vesicovaginal fistula)

Question 21

Palliative therapy what’s the stage we gonna use it for ?

Answer 21

Stage 3 , 4

Question 22

What’s the palliative therapy?

Answer 22

1. Some suitable for extensive surgery.
2. Some suitable for chemotherapy
3. Good nursing care
4. Analgesia-must be used in sufcient amount to —– pain ( Pethidine, Morphine).
5. Antiemetic if necessary.
6. IV drip and parenteral feeding.
7. Urinary Catheterization.
8. Other measures for symptom relief