Cervical Screening

Question 1

Which cancers can be caused by high risk HPV?

Answer 1

Cervix
Penis
Vulva/vagina
Anus
Mouth
Oropharynx

Question 2

How do the HPV test and cytology test differ?

Answer 2

HPV test

• machine
• identifies infection (could be transient or CIN associated)
• sensitive

Cytology

• human interpretation
• identifies cellular changes (low grade - persisting infection/CIN1; high grade - CIN2/3)
• specific

Question 3

What happens if a sample comes back positive for high risk HPV?

Answer 3

If cytology is normal - repeat test in 1 year

Dyskaryosis - refer to colposcopy

Question 4

What are the high risk types of HPV?

Answer 4

Mainly 16 & 18, but also 31 and 45

Question 5

How is CIN treated?

Answer 5

LLETZ
Thermal coagulation
Laser ablation

Question 6

What does follow up after treatment of CIN involve?

Answer 6

Follow up LBC at 6 months for cytology and high risk HPV