What is cell continuity?
All cells develop from pre-existingcells
What are chromosomes?
Coiled threads of DNA and protein that become visible in the nucleus during cell division
What is a gene?
A section of DNA containing the instructions for the formation of a protein
All the genes in an organism make up its genome
What is a haploid cell?
A cell with one set of chromosomes
e.g. sperm cells
Symbolised with the letter ‘n’
What is a diploid cell?
A cell with two sets of chromosomes
e.g. cheek cell
Symbolised with the ‘2n’
What is a homologous pair?
2 chromosomes of similar size with the same gene sequence
In diploid cells, one chromosome from each pair comes from the mother and one from the father
What is the cell cycle?
Changes that take place in a cell during the period between one cell division and the next
What is interphase?
Explain interphase
The phase in the cell cycle when the cell is not dividing
-Longest phase of cell cycle
-Chromosomes are elongated and form part of a mass called chromatin
-The early stage produces organelles (mitochondria and chloroplasts) and enzymes and proteins needed for growth
-Chromosomes produce replicates of themselves at the end
What is mitosis
A form of nuclear division in which one nucleus divides to form two nuclei, each containing the same number of chromosomes with identical genes
Briefly explain mitosis
-New cells formed are called daughter cells
-Takes place in cells not associated with the reproductive system (somatic cells)
-Interphase, prophase, metaphase, anaphase, telophase
(I Party Monday And Tuesday)
Explain prophase
DIAGRAM***
-Chromatin starts to condense
-Chromosomes become visible as double stranded structures
-The strands are held together by a centromere
-Each strand has identical genes
-Nucleolus disappears
-Spindle fibres appear in cytoplasm
-Nuclear membrane starts to break down
Explain Metaphase
-Nuclear membrane completes full breakdown
-Spindle fibres from each pole attaches to each centromere
-Chromosomes line up across middle of the cell
Explain Anaphase
-Spindle fibres contract
-Centromeres split
-One chromosome is pulled to each pole
-Anaphase is the shortest phase
Explain Telophase
-Chromosomes lengthen and become hard to distinguish
-Spindle fibres break down
-Nucleoli and nuclear membranes begin to reform
- Original nucleus has divided into two nuclei (same set of genes but half the organelles and biomolecules than parent cell)
Explain how cells divide in animal cells
A cleavage furrow appears and becomes deeper until the cell splits in two
Explain how cells divide in plant cells
-Rigid cell wall prevents cleavage furrow from forming
-Vesicles (membrane-enclosed sacs) gather in the area between the two nuclei
-Vesicles contain cellulose to form a new cell wall
-Vesicles form the cell plate
-Cell plate enlarges to join cell membrane around the cell
-Two cell walls form with a middle lamella between them
What is the function of mitosis in unicellular organisms
-Method of asexual reproduction
What is the function of mitosis in multicellular organisms
-Used for growth and repair of cells in animals and plants
-Allows single celled zygote to become an embryo
What is cancer?
A group of disorders in which certain cells lose their ability to control the rate of mitosis and the number of times it takes place
-Mitosis is normally tightly controlled
-Uncontrolled mitosis produces a tumour (mass of cells)
What are benign tumours?
-Not life-threatening
-Cells stop dividing after some time
-Do not invade other tissues
-Can be surgically removed
-E.g. warts, skin tags, most breast tumours
What are malignant tumours?
-May be life-threatening
-Can move from one place to another in the body (metastasis)
-Cells divide indefinitely
What are the causes of cancer?
-Normal genes mutate to form cancer causing genes (oncogenes)
-Carcinogens cause these mutations, e.g. cigarette smoke, asbestos
What treatment types are available for cancer?
-Surgery
-Radiation
-Chemotherapy
What is meiosis?
A form of nuclear division in which the 4 daughter nuclei contain half the chromosome number of the parent nucleus