CH5

Question 1

Clacium channel blocker

Answer 1

cadmium

Question 2

blocks sodium channels

Answer 2

tetrodotoxin

Question 3

Two ways effect of presynaptic Ca++ on NT release have been shown

Answer 3

Using Ca++ sensitive fluorescent dyes:

1. microinjection of Ca++ in presyn terminal w/o presyn action potential causes NT release
2. Injection of Ca++ chelators prevents NT release when there is AP

Question 4

Ca++ chelator

Answer 4

buffers calcium

Question 5

In NT release, Ca++ is a ______

Answer 5

second messenger

Question 6

Protein that probably tethers reserve pool

Answer 6

synapsin

Question 7

Allows synapsin to dissociate from vesicles

Answer 7

CaMKII phosphorylates synapsin

Question 8

synaptotagmin is found

Answer 8

in the membranes of synaptic vesicles

Question 9

EPC equation

Answer 9

gACh(Vm - Erev)

Question 10

Metabotropic receptors also called

Answer 10

G-protein-coupled receptors