purines
- double-ring structures
pyrimidines
- single-ring structures
Chargaff’s Rule
-AT/GC
Which end is the phosphate group bonded?
5` end
Which end is the hydroxyl ground bonded?
3` end
Rosalind Franklin’s work suggested what DNA structure?
double helix
DNA helicase
unwinds the double helix
topoisomerase (gyrase)
prevents twisting as DNA unwinds
single-stranded binding proteins
prevent separated strands from coming together again behind DNA helicase