Neurodevelopmental Disorders
- includes?
Affecting children and adolescents that involve impaired brain functioning or development; affect childs psych, cog, social, or emotional development
• Includes: Autism spectrum, intellectual disability, specific learning disorder, communication disorders, ADHD
Abnormal behavior in children (2)
- cultural study
Prevalence of Disorders in Children and Adolescents:
Depression survey
found 7% of boys and 14% of girls ages 12-17 suffered from major depression in preceding 6 months
Risk factors for childhood disorders
• Include genetics, enviro, and family
• Children of depressed parents also stand higher risk of getting disorder
• Ethnic minority children higher risk for problems like ADHD, anxiety, depression (reason unknown)
• Boys at greater risk for many disorders ranging from autism to hyperacticity to elimination disorders; also anxiety and depression
However, in adolescents anxiety and mood disorders become more common in girls
Childhood Abuse
• Physical and sexual abuse linked to increase risk of: ADHD, anxiety, depression, sub abuse, PTSD, conduct disorder
effects include: low self-esteem, depression, immature behaviors (bed wetting, thumbsuching), suicide thinking, poor school performance, failure to venture beyond the home. These behaviors often lead into adulthood
• 8% of men and 20% of women had suffered sexual abuse before 18
• More than 1.5 million children in US are victims of child abuse or neglect
• Between 1,000 and 2,000 children in US die each year from abuse more than twice the rate of Great Britain, France, Canada, or Japan
Autism (1)
Chronic, life-long condition; placed in ASD
• Term first used in 1906 by Eugen Bleuler to refer to a weird style of thinking among ppl with schizo
• Autistic thinking is the tendency to view oneself as the center of the universe; believe that external events somehow refer to oneself
• 1943, Leo Kanner applied diagnosis of early infantile autism to a group of disturbed children who couldn’t relate to others, creating autistic aloneness
- 5 times as common in boys as girls
•Signs of disorder start at 12 to 18 months – often “good” babies; however as they develop they begin to reject physical affection; speech then falls behind. Signs of social detachment often being during first year (failure to look at ppl’s face)
• Disorder diagnosed reliably by age 2 or 3 but avg autistic child doesn’t get diagnosis until age 6
* Delays are bad; earlier the better
Autism Spectrum Disorder
developmental disorder characterized by significant deficits in communication and social interaction, as well as development of restricted or fixated interests and repetitive behaviors
• Clinicians need to rate severity of ASD as severe, moderate, or mild
• Asperger’s disorder and childhood disintegrative disorder used in prev DSM to describe distinct spectrum disorders but now are classified as forms of ASD
Asperger’s disorder
pattern of behavior involving social awkwardness and repetitive behaviors without significant language or cognitive deficits assoc with more sever forms of ASD. They don’t show deficits in intellectual, verbal and self-care. They may have remarkable verbal skills (read paper by 5) and develop an obsessive interest in narrow topics.
Childhood disintegrative disorder
significant loss (disintegration) of prev acquired skills in areas like understanding or using language, social or adaptive functioning, bowel or bladder control, play, motor skills. Rare and appears more in boys.
Autism Spectrum Disorder Prevalence
• Rates rising over past 20 years
- more than 1 million total- affected by some form
• 2013 estimated 1 in 50 children (2%) in US
- not sure; one cause is couples are postponing having kids more than other generations (Autism linked in children with older fathers)—Still risk is low, only 2% for father’s 40+
- MMR vaccine (measles, mumps, rubella)
Autism features -3 core
Theoretical Perspective of Autism
Treatment for autism
• Early intensive behavioral programs that apply learning principles in child’s environment can improve learning and language skills–The earler the treatment is started (before age 5) and the more intense the better results
• Applied behavior analysis (ABA) learning based model- no other has had comparable results; uses operant conditioning where parents and therapists engage in the painstaking work, systematically using rewards and punishments to increase child’s ability to attend to others, play with others, develop academic skills, and reduce or eliminate self-mutilation
• O. Ivar Lovaas study: showed impressive gains in autistic children who go more than 40 hours of treatment for each week for two years
-benefit from early training focusing on imitation skills
- antipsych drugs to control disruptive behavior but work better when combined with learning treatment
• Small subset who appear to overcome disorder
Intellectual Disability
(formerly called MR) generalized delay or impairment in development of intellectual and adaptive abilities; lack basic conceptual, social, and practical skills of daily living. Children tend to have deficits in reasoning and problem solving, abstract thinking, judgment, school performance
- 1%
- before 18; lifelong course however many improve over time
- basis of low IQ score and impaired adaptive functioning resulting in impairment in meeting expected standards of independent functioning and social responsibility. Impairments involve difficulty preforming common tasks of daily life in three domains:
1. Conceptual (skills relating to use of language, reading, writing, math)
2. Social (skills relating to awareness of other peoples experiences, communicate with others, form friendships)
3. Practical (ability to meet personal care need, fulfill job responsibilities, manage money)
- based on severity; Level of severity is based on child’s adaptive functioning
• Most with ID (85%) fall into mild range—able to meet basic academics like reading simple passages; as adults they are capable of independent functioning
Causes of ID (2)
Chromosomal Abnormalities
Down syndrome, Klinefelter’s syndrome, Turner’s syndrome
Down syndrome
• Most frequent ID; condition cause by extra chromo on 21st pair (resulting in 47 chromos rather than 46) and characterized by intellectual developmental disorder and physical abnormalities
• Occurs in 1 in 800 births
• Happens when 21st pair in either egg or sperm fails to divide normally resulting in extra chromo
• Expectant couples in mid 30’s; Down syndrome can be traced to mother’s egg in about 90% of cases
- Round broad face, flat nose, small downward sloping folds of skin at inside corners of eyes—gives impression of slanted eyes. A protruding tongue, small arms, curved fifth finger
- many suffer from physical probs like malformations of heart and respiratory difficulties; almost all have ID; LE is 49
- Tend to be uncoordinated, lack muscle tone, suffer memory deficits especially verbal info presented; Despite disabilities most can learn to read, write, and perform simple math
Klinefelter’s syndrome
• Abnormalities on sex chromos which can result in an ID
Occurs only in males – presence of extra X chromo resulting in an XXY pattern
• Only 2 per 1,000 male births
• These men fail to get secondary sex charactersitics resulting in breasts, small testes, low sperm, and infertility.
• Often don’t know they have it until tested for fertililiy
Turner’s syndrome
Genetic abnormalities
Fragile X, Phenylketonuria (PKU)
Fragile X syndrome
Most common genetic cause; affects 1 of 1,000 to 1,500 males and 1 of 2,000 to 2,500 females
Second common form of ID after down syndrome
• Caused by mutation on single gene in area of X chromo that appears fragile
• range from mild learning disorders to ID so profound that they can hardly speak or function
• Females normally have two X chromos; males one. Females two X’s provide protection against disorder if defective gene turns up –which only leads to mild disability
• Many males and females carry the fragile X mutation without showing any signs
Phenylketonuria (PKU)
Prenatal tests - 2