Protein receptors located in the plasma membranes of defensive cells (phagocytes)
Toll-like receptors (TLR)
Substances that increase phagocytosis.
Opsonins
What is a complement?
Protein that get rid of microorganisms.
First line of defense against microorganisms
Defense in the respiratory system.
Attaches to the cilia in the lungs and destroys them
B. pertussis (Whooping cough)
Second line of defense against microorganisms
3 types of formed elements?
First to arrive at site of infection. Perform phagocytosis.
Neutrophils
2 cell types that kill extraceularly?
- Natural killer lymphocytes
Antimicrobial substances, against pathogens.
Nonspecific chemical defenses
How long does it take to make antibodies?
About 2 weeks
Defenses in digestive system
Monocytes that cross to the tissues
macrophages
Proteins that non specifically get rid of microorganisms.
complement
Complement activation results in:
Antiviral proteins produced by animal cells after viral stimulation.
Interferons (IFN)
A type of antimicrobial peptides (AMP) produced by neutrophils, macrophages.
Defensins
Phagocytosis
Name 3 phagocytes:
What types of defense mechanisms do the innate immune system use to combat extracellular pathogens?
What types of defense mechanisms do the innate immune system use to combat intracellular pathogens?
-Interferons
Combats worms in blood?
Eosinophils
Results when chemicals called pyrogens trigger the hypothalamus to increase the body’s core temperature
Fever
Anything that increases temperature.
Pyrogens