what blood vessel has the most smooth muscle fibers + creates greatest resistance to tissue blood flow
arterioles
what blood vessel is located at the origin of each true capillary + opens/closes cyclically for intermittent perfusion
precapillary sphincters
what blood vessel is responsible for vasomotion
pre-capillary sphincters + metarterioles
what blood vessels have the lowest pressure
venules
what blood vessels have the smallest diameter
capillaries
what blood vessels have intermittent bands of smooth muscle
metarterioles
what is vasomotion
intermittent contraction/relaxation of precapillary sphincters to regulate specific flow amount + duration
what is the main factor driving the opening/closing of precapillary sphincters
O2 concentration in the tissue
what are intracellular clefts
slit pores where 2 endothelial cells meet up
what is the purpose of intracellular celfts
passage for water + water soluble particles
plasmalemmal vesicles (caveolae)
indentations lined with special protein receptors
basement membrane
thin external covering
special capillary beds in brain
tight junctions that contribute to BBB
special capillary beds in muscle and CT
slit pores 6-7 nm
special capillary beds in GI tract
slightly larger slit pores than muscles
special capillary beds in liver
wide open clefts that allow plasma proteins through
special capillary beds in kidney
normal sized slit pores to allow water/solute through
DOES IT CROSS THE CAPILLARY MEMBRANE
MAKE TABLE
what makes up the interstitium
collagen fibers, proteoglycan filaments, interstitial gel, + rivulets
what are collagen fibers for
structure and tensile strength
proteoglycan filaments
tiny coiled molecules of hyaluronic acid and protein
interstitial gel
the fluid trapped in the reticular filaments that has to diffuse slowly through the available space
rivulets
contain interstitial fluid that flows to collagen
lymph functions