a. Renin
b. Aldosterone
c. Angiotensin
d. Antidiuretic hormone (ADH)
ANS: D. Antidiuretic hormone (ADH)
ADH is released in response to increased osmolality and decreased volume of intravascular fluid; it promotes
water retention in the renal system by increasing the permeability of renal tubules to water. Renin release is
stimulated by diminished blood flow to the kidneys. Aldosterone is secreted by the adrenal cortex. It enhances
sodium reabsorption in renal tubules, promoting osmotic reabsorption of water. Renin reacts with a plasma
globulin to generate angiotensin, which is a powerful vasoconstrictor. Angiotensin also stimulates the release
of aldosterone.
ANS: A. Fever
Fever leads to great insensible fluid loss in young children because of increased body surface area relative to
fluid volume. The mechanically ventilated child has decreased fluid requirements. Congestive heart failure is a
case of fluid overload in children. Increased intracranial pressure does not lead to increased fluid requirements
in children
ANS: C. Immature kidney functioning
The infants kidneys are functionally immature at birth and are inefficient in excreting waste products of
metabolism. Infants have a relatively high body surface area (BSA) compared with adults. This allows a higher
loss of fluid to the environment. A higher metabolic rate is present as a result of the higher BSA in relation to
active metabolic tissue. The higher metabolic rate increases heat production, which results in greater insensible
water loss. Infants have a greater exchange of extracellular fluid, leaving them with a reduced fluid reserve in
conditions of dehydration.
ANS: C. 1200
For the first 10 kg of body weight, a child requires 100 ml/kg. For each additional kilogram of body weight, an
extra 50 ml is needed.
10 kg 100 ml/kg/day = 1000 ml
4 kg 50 ml/kg/day = 200 ml
1000 ml + 200 ml = 1200 ml/day
Eight hundred to 1000 ml is too little; 1400 ml is too much.
ANS: C. Water depletion
These clinical manifestations indicate water depletion or dehydration. Edema and weight gain occur with water
excess or overhydration. Sodium or potassium excess would not cause these symptoms.
ANS: D. Dry, sticky mucous membranes
Dry, sticky mucous membranes are associated with hypernatremia. Hyperreflexia is associated with
hyperkalemia. Abdominal cramps, weakness, dizziness, nausea, and apprehension are associated
hyponatremia. Cardiac dysrhythmias are associated with hypokalemia.
ANS: A. Decreased hematocrit
The excess water in the circulatory system results in hemodilution. The laboratory results show a falsely
decreased hematocrit. Laboratory analysis of blood that is hemodiluted reveals decreased serum osmolality and blood urea nitrogen. The urine specific gravity is variable relative to the childs ability to correct the fluid
imbalance.
ANS: D. Neuromuscular irritability
Neuromuscular irritability is a clinical manifestation of hypocalcemia. Nausea and vomiting occur with
hypercalcemia and hypernatremia. Weakness, fatigue, and muscle hypotonicity are clinical manifestations of
hypercalcemia.
ANS: B. Hypotonic dehydration
Hypotonic dehydration occurs when the electrolyte deficit exceeds the water deficit, leaving the serum
hypotonic. Isotonic dehydration occurs in conditions in which electrolyte and water deficits are present in
balanced proportion. Hypertonic dehydration results from water loss in excess of electrolyte loss. This is the
most dangerous type of dehydration. It is caused by feeding children fluids with high amounts of solute. Hyperosmotic dehydration is another term for hypertonic dehydration.
ANS: B. 50 to 90 ml/kg
Moderate dehydration is defined as a fluid loss of between 50 and 90 ml/kg. Mild dehydration is defined as a
fluid loss of less than 50 ml/kg. Weight loss up to 5% is considered mild dehydration. Weight loss over 15% is
severe dehydration.
b. Hemoconcentration to reduce
cardiac workload
c. Fluid shift from interstitial space to intravascular space
d. Vasodilation of peripheral arterioles to increase perfusion
ANS: C. Fluid shift from interstitial space to intravascular space
Compensatory mechanisms attempt to maintain fluid volume. Initially, interstitial fluid moves into the
intravascular compartment to maintain blood volume. Aldosterone is released to promote sodium retention and
conserve water in the kidneys. Hemoconcentration results from the fluid volume loss. With less circulating
volume, tachycardia results. Vasoconstriction of peripheral arterioles occurs to help maintain blood pressure.
a. Tachycardia
b. Slow respirations
c. Warm, flushed skin
d. Decreased blood pressure
ANS: A. Tachycardia
Shock is preceded by tachycardia and signs of poor tissue perfusion and decreased pulse oximetry values. Respirations are increased as the child attempts to compensate. As a result of the poor peripheral circulation,
the child has skin that is cool and mottled with decreased capillary refilling after blanching. In children,
lowered blood pressure is a late sign and may accompany the onset of cardiovascular collapse
ANS: D. Dry mucous membranes and generally ill appearance
A good predictor of a fluid deficit of at least 5% is any two four factors: capillary refill of more than 2 seconds, absent tears, dry mucous membranes, and ill general appearance. Weight loss is associated with fluid deficit, but the degree needs to be quantified. Heart rate is usually elevated. Skin elasticity is decreased, not increased. The anterior fontanel is depressed.
a. Oliguria
b. Weight loss
c. Irritability and seizures
d. Muscle weakness and cardiac dysrhythmias
ANS: C. Irritability and seizures
Irritability, somnolence, headache, vomiting, diarrhea, and generalized seizures are manifestations of water
intoxication. Urinary output is increased as the child attempts to maintain fluid balance. Weight gain is usually
associated with water intoxication. Muscle weakness and cardiac dysrhythmias are not associated with water
intoxication.
a. Metabolic acidosis
b. Respiratory alkalosis
c. Metabolic and respiratory acidosis
d. Metabolic and respiratory alkalosis
ANS: D. Metabolic and respiratory alkalosis
The major symptoms and signs of alkalosis include nervous system stimulation and excitement, including
overexcitability, nervousness, tingling sensations, and tetany that may progress to seizures. Acidosis (both
metabolic and respiratory) has clinical signs of depression of the central nervous system, such as lethargy, diminished mental capacity, delirium, stupor, and coma. Respiratory alkalosis has the same symptoms and
signs as metabolic alkalosis
ANS: B. Weigh diapers after each void.
Weighing diapers will provide an estimate of urinary output. Each 1 g of weight is equivalent to 1 ml of urine. Having parents estimate output would be inaccurate. It is difficult to estimate how much fluid is in a diaper. The urine collection device would irritate the childs skin. It would be difficult for a toddler who is not toilet
trained to sit on a potty chair 30 minutes after eating
a. Gently tap over the site.
b. Apply a cold compress to the site.
c. Raise the extremity above the level of the body.
d. Use a rubber band as a tourniquet for 5 minutes.
ANS: A. Gently tap over the site.
Gently tapping the site can sometimes cause the veins to be more visible. This is done before the skin is
prepared. Warm compresses (not cold) may be useful. The extremity is held in a dependent position. A
tourniquet may be helpful, but if too tight, it could cause the vein to burst when punctured. Five minutes is too
long.
ANS: B. Check the insertion site frequently for signs of infiltration.
The nursing responsibility for IV therapy is to calculate the amount to be infused in a given length of time; set
the infusion rate; and monitor the apparatus frequently, at least every 1 to 2 hours, to make certain that the
desired rate is maintained, the integrity of the system remains intact, the site remains intact (free of redness, edema, infiltration, or irritation), and the infusion does not stop. Insertion sites do not need to be changed every
24 hours unless a problem is found with the site. This exposes the child to significant trauma. A minidropper
(60 drops/ml) is the recommended IV tubing in pediatric patients. Intravenous sites should be protected. This
may require soft restraints on the child.
ANS: B. End the infusion and notify the practitioner.
A vesicant causes cellular damage when even minute amounts escape into the tissue. The intravenous infusion
is immediately stopped, the extremity is elevated, the practitioner is notified, and the treatment protocol is
initiated. The applying of heat or ice depends on the fluid that has extravasated. The catheter is left in place
until it is no longer needed.
a. You do not need to pierce the skin for access.
b. It is easy to use for self-administered infusions.
c. The patient does not need to limit regular physical activity, including swimming.
d. The catheter cannot dislodge from the port even if the child plays with the port site.
ANS: C. The patient does not need to limit regular physical activity, including swimming.
No limitations on physical activity are needed. The child is able to participate in all regular physical activities,
including bathing, showering, and swimming. The skin over the device is pierced with a Huber needle to
access. Long-term central venous access devices are difficult to use for self-administration. The port is placed
a. Hypertension
b. Pain at the entry site
c. Fever and general malaise
d. Redness and swelling at the entry site
ANS: C. Fever and general malaise
Fever, chills, general malaise, and an ill appearance can be signs of bacteremia and require immediate
intervention. Hypotension would be indicative of sepsis and possible impending cardiovascular collapse. Pain,
redness, and swelling at the entry site indicate local infection
ANS: A. Saline
The recommended solution for flushing venous access devices is saline. The turbulent flow flush with saline is
effective for catheters larger than 24 gauge. The use of heparin does not increase the longevity of the venous
access device. In 24-gauge catheters, heparin may offer an advantage. Alteplase is used for treating catheterrelated occlusions in children. The heparin and saline combination does not offer any advantage over saline or
heparin individually.
a. I should have my child wear a protective vest when my child wants to participate in contact sports.
b. I should apply pressure to the entry site to the vein, not the exit site, if the VAD is accidentally
removed.
c. I can expect my child to have feelings of general malaise for 1 week after the VAD is inserted.
d. I should give my child a sponge bath for the first 2 weeks after the VAD is inserted; then I can
allow my child to take a bath.
ANS: B. I should apply pressure to the entry site to the vein, not the exit site, if the VAD is accidentally
removed.
The parents of a child with a VAD should be taught to apply pressure to the entry site to the vein, not the exit
site, if the VAD is accidentally removed. The child should not participate in contact sports, even with a
protective vest, to prevent the VAD from becoming dislodged. General malaise is a sign of an infection, not an
expected finding after insertion of the VAD. The child can shower or take a bath after insertion of the VAD;
the child does not need a sponge bath for any length of time.
a. Osmotic
b. Secretory
c. Cytotoxic
d. Dysenteric
ANS: D. Dysenteric
Dysenteric diarrhea is associated with an inflammation of the mucosa and submucosa in the ileum and colon
caused by infectious agents such as Campylobacter, Salmonella, or Shigella organisms. Edema, mucosal
bleeding, and leukocyte infiltration occur. Osmotic diarrhea occurs when the intestine cannot absorb nutrients
or electrolytes. It is commonly seen in malabsorption syndromes such as lactose intolerance. Secretory diarrhea
is usually a result of bacterial enterotoxins that stimulate fluid and electrolyte secretion from the mucosal crypt
cells, the principal secretory cells of the small intestine. Cytotoxic diarrhea is characterized by the viral
destruction of the villi of the small intestine. This results in a smaller intestinal surface area, with a decreased
capacity for fluid and electrolyte absorption.