chapter 24

Question 1

Halogenation

Answer 1

reagents: Cl2/Br2 and FeCl2
Replaces H

Question 2

Nitration

Answer 2

Reagents: HNO3, H2SO4
-h gets replaced by NO2

Question 3

Sulfonation

Answer 3

Reagents: SO3, H2SO4
H gets replaced by SO3H

Question 4

Friedel Craft Alkylation

Answer 4

Cl-R and AlCL3
-H gets replaced with R group
BEWARE: must be SP3, Rearrangement can occur

Question 5

FC Acylation

Answer 5

Acyl Chloride rather than alkyl chloride
-Acid chloride and ALCl3, end of R goes where H was
-can help pervent rearrangement (Reduce O with ZN or N2H4)

Question 6

Side Chain Oxidation

Answer 6

any r-group with benzylic H can be oxidized to COOH with h2CRO4 or KMNo4

Question 7

NO2 to NH2

Answer 7

use H2/Pd

Question 8

Amine Oxidation

Answer 8

NH2 to N2CL (NaNO2 HCL)