The pentose phosphate pathway produces…
NADPH, ribose 5-phosphate, and provides an entry point for dietary pentose sugars
NADPH
source of biosynthetic reducing power of fatty acids, steroid, etc.
first phase of PPP
oxidative generation of NADPH; 3irreversible rxns
second phase of PPP
nonoxidative interconversion of a variety of sugars; 5 reversible rxns
fatty acid synthesis in..
liver, adipose tissues, and mammary glands
steroid synthesis in…
adrenal gland, testes, and ovaries
rate-limiting step of PPP
first reaction; G6P by glucose 6-phosphate dehydrogenase
rate limiting step is controlled by..
level of NADP+
four distinct modes of the PPP