Chapter 3 Data Interpretation

Question 1

Causes of Microcytic Anaemia (3)

Answer 1

Iron deficiency
Thalassaemia
Sideroblastic Anaemia

Question 2

Causes of Normocytic Anaemia (4)

Answer 2

Anaemia of chronic disease
acute blood loss
Haemolytic anaemia
Chronic renal failure (reduced EPO)

Question 3

Macrocytic Anaemia (5)

Answer 3

Megaloblastic anaemia (B12/Folate deficiency/pernicious)
EToH excess
Liver disease (non EToH)
HypoT4
Haematological Diseases
    - Myeloproliferative
    - Myelodysplastic
    - Multiple Myeloma

Question 4

Causes of Neutrophilia (3)

Answer 4

Raised WCC (4-11)

1. Bacterial infection
2. Tissue damage (inflam/infarct/Ca)
3. Steroids

Question 5

Causes of Neutropenia (4)

Answer 5

Low WCC (4-11)

1. Viral Infection
2. Chemo/Radio T
3. Clozapine (agranulocytosis)
4. Carbimazole (for hyperT4)

Question 6

Causes of Lymphocytosis (3)

Answer 6

Raised Lymphocytes (1.3-3.5)

1. Viral INfection
2. Lymphoma
3. CLL- Chronic Lymphocytic Leukaemia

Question 7

Causes of Thrombocytopenia:
2 categories
1. (3)
2. (5)

Answer 7

Low platelets (s: Myelodysplasia, Myelofibrosis, 
         Myeloma

2. Increased Destruction
    A. Heparin
    B. Hypersplenism
    C. DIC
    D. ITP
    E. HUS/TTP

Question 8

Causes of THrombocytosis
2 categories
1. (3)
2. (1)

Answer 8

High Platelets (>400)
1. Reactive
    A. Bleeding
    B. Tissue Damage
    C. Post splenectomy

2. primary:
   A. myeloproliferative disorders