chapter 4-3

Question 1

heparin-induced thrombocytopenia

Answer 1

plt destruction 2ndary to heparin use

Question 2

DIC

Answer 2

widespread microthrombi-ischemia/infarction

LABS- dec plt count, incre PT/PT, dec of fibrinogen. Microagiopathic hemolytic anemia, INCREASE D_DIMER

Question 3

Significant lab finding in DIC differ from

Answer 3

D- DImer from splitting of cross linked fibrin NOT fibrinogenin

Question 4

fibrinolysis normally

Answer 4

TPA converts plasminogen to plasmin cleaves fiibin and serum fibrinogen and helps with PTT aggregation

Question 5

what activates/inactivates plasmin

Answer 5

activates- tpA

inactivates alpha 2 antiplasmin

Question 6

fibrinolysis problems

Answer 6

increas PT and PTT = plasmin kils coagulation factors.
increase BT
normal PLts
NO INCREASE IN D-DIMER