1
Q
What causes a ligand-gated channel to open
A
A specific ligand binds to a receptor
2
Q
What causes a voltage-gated channel to open
A
A specific membrane potential is reached
3
Q
What are the two things an activated G-protein can do?
A
Open ion channel
Activate a 2nd messenger system
4
Q
What are the two second messengers we discussed in class?
A
cAMP and PIP2
5
Q
What is the difference between an activated G-protein and an inactive G-protein
A
Active has a GTP
Inactive has a GDP
6
Q
What does cAMP do?
A
Activates PKA
7
Q
What does PIP2 do
A
Splits PLC into DAG and IP3
8
Q
Once a G-protein is activated what part(s) dissociate
A
Alpha and GTP
PE 220
flashcards
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