chapter 5 biochem

Question 1

myoglobin located

Answer 1

muscle tissue cardiac and skkeletal

Question 2

myoglobin functions

Answer 2

transports o2 from hemoglobin to mitochondria
storage for oxygen

Question 3

heme group

Answer 3

prosthetic group found in both hemoglobin and myoglobin

Question 4

heme group function

Answer 4

allows protiens to bind to oxygran

Question 5

number of heme group sin myoglobin

Answer 5

1 heme group

Question 6

number of myoglobins in hemoglobins

Answer 6

4

Question 7

heme group spcial fetaure that allows in to bind to oxygen

Answer 7

contains fe 3+

Question 8

similarities between myoglobin and hemoglobin

Answer 8

2,3 structure
same heme prosthetic group
oxygen transport

Question 9

differences between myoglobin and hemoglobin

Answer 9

prmary structures
location
o2 affinity

Question 10

myoglobin subunit

Answer 10

monomer

Question 11

hemoglobin subunit

Answer 11

tetramer

Question 12

variant amino acids

Answer 12

can be replaced with no changes

Question 13

conserved amino acids

Answer 13

can be replaced with similar ones and no changes will occur

Question 14

invariant

Answer 14

cannot be changed or else it will cause chage in sturcutre and fuction

Question 15

hemoglobin pirmary strucutre

Answer 15

sequence of amino acids

Question 16

hemoglobin seocndary structure

Answer 16

alpha helices

Question 17

hemoglobin tertiery

Answer 17

side chain interactions with each subunit

Question 18

quaternary

Answer 18

2 alpha 2 beta subunits

Question 19

coopertivity

Answer 19

when protien completely changes its shape after binding

Question 20

myoglobin coopertivity

Answer 20

does not occur

Question 21

hemoglobin coopertivity

Answer 21

does occur

Question 22

hemoglobin conformations

Answer 22

tense and relaxed

Question 23

tense state in hemoglobin

Answer 23

deoxy
low o2
tissues

Question 24

relaxed state in hemo

Answer 24

oxy
high o2 affinity
lungs

Question 25

bohr ph effect in tissues

Answer 25

cell resp. produces acid ph decrease hemo becomes tense o2 released

Question 26

bohr ph effect in lungs

Answer 26

ph increase hemo shifts to relaxed o2 binds to hemo

Question 27

bpg binding

Answer 27

only to tense hemo promotes o2 release aka decrease in affonty helps oxygen delivery to tissues

Question 28

three types of cytoskeleton filaments

Answer 28

actin intermediate microtubules