Which types of malignant neoplasia have been associated with human papilloma virus?
cervix, vulva, anal canal, head and neck
Which part of the papillomavirus interact with PFGFR?
E5
How does the papillomavirus affect P53 function in the cell?
E6 is an ubiquitin ligase, ultimately resulting in degradation of p53
How does the presence of papillomavirus influence the function of pRb?
E7 binds pRB, which targets pRB for degradation.