Chapter 6- Medications

Question 1

Antiplatelets

Answer 1

Primary and Secondary stroke prevention; duel therapy not for longterm due to risk of bleeding

Question 2

Aspirin

Answer 2

Primary prevention; Cyclooxygenase inhibitor; dose 81-325; irreversible, inhibits for the life of platelet (5-7 days)—–common risk=GI bleed—avoid NSAIDs

Question 3

Aggrenox (Dipyridamole/aspirin)

Answer 3

Secondary prevention;PCE inhibitor; dose: 200/25mg BID; irreversible (5-7days); poorly tolerated–causes headache in 40%

Question 4

Clopidogrel (Plavix)

Answer 4

secondary prevention; Adenosine diphosphate inhibitor; dose: 75mg daily; PPI decrease plavix effects;

Question 5

Ticlopidine (Ticlid)

Answer 5

secondary prevention; 250 mg BID; irreversible, last 5-7 days; GI intolerance, neutropenia, aplastic anemia