Daunorubicin (lifetime dose)
550mg/m2 (400 with radiation)
Bleomycin (lifetime dose)
400 units
DOXORUBICIN (lifetime dose)
550mg/m2
Methotrexate (precaution)
alkalize urine to prevent crystallization.
PERTUZUMAB (perjeta, black box warning)
cardiac dysfunction
SODIUM THIOSULFATE (use)
“For the treatment of extravasation† of cytotoxic drugs (e.g., cisplatin, dacarbazine, mechlorethamine, mustine)*
“
TRASTUZUMAB (Herceptin) considerations
Needs Echo prior to start for EF measurement and or MUGA; not compatible with clindomycin, lasix, levofloxan, morphine, zofran. “
VANCOMYCIN (treats)
gram + infections