Chemotherapy Classes

Question 1

Name the 3 classes of alkylators

Answer 1

1. Nitrogen mustards
2. Nitrosoureas
3. Other alkylators

Question 2

Name the 5 Nitrogen mustards (alkylators)

Answer 2

1. Mechlorethamine
2. Melphalan
3. Cyclophosphamide
4. Ifosfamide
5. Chlorambucil

Question 3

Name the 2 Nitrosoureas (alkylators)

Answer 3

1. Lomustine

2. Streptozotocin

Question 4

Name the 2 Other aklylators

Answer 4

1. Dacarbazine

2. Procarbazine

Question 5

Name 3 antitumor antibiotics

Answer 5

1. Doxorubicin
2. Mitoxantrone
3. Actinomycin D

Question 6

Name the 4 Antimetabolites

Answer 6

1. Cytosine arabinoside
2. Methotrexate
3. Gemcitabine
4. 5-FU

Question 7

Name the 2 Groups of Antimicrotubule agents and the five drugs associated with them

Answer 7

1. Taxanes (Paclitaxel, Docetaxel)

2. Vinca Alkaloids (Vincristine, Vinblastine, Vinorelbine)

Question 8

Name 2 topoisomerase inhibitors

Answer 8

(Epipodophyllotoxins)

1. Etoposide
2. Teniposide

Question 9

Name the 4 other drugs (in 3 categories) that WM places into the “other” group

Answer 9

1. platinums (carbo/cis)
2. Hydroxyurea
3. L-asparaginase