Cholesterol

Question 0

how is cholesterol transported?

Answer 0

transported as VLDL

Question 1

what is the rate limiting step in cholesterol biosynthesis?

Answer 1

HMG-CoA reductase

many drugs developed to attack this enzyme

Question 2

What catalyzes the esterification of cholesterol?

Answer 2

Acyl CoA cholesterol Acyl Transferase (ACAT)

Question 3

Cholesterol is precursor for steroid hormones

Answer 3

examples 
Glucocorticoids 
Mineralcorticoids 
Androgens
Estrogens 
Progestins

Question 4

Gall stones

Answer 4

if CH crystalizes due to increased CH:phospholipid ratio

Question 5

Atherosclerosis

Answer 5

Foam cells form from Macrophages that have been attracted due to inflammation from constant oxidation of cholesterol in the arterial intima

Question 6

Statins inhibit

Answer 6

HMG-CoA reductase