1
Q
Acetylcholine
A
- effects are opposite of noradrenaline
- broken down by cholinesterases
- used as miotic in cataract surgery
- has muscarinic and nicotinic activity
- adverse effects:1)hypotension 2)bronchospasm 3)hyperthyroidism
2
Q
Atropine
A
- muscarinic antagonist (acts similar to adrenergic agonist)
- block post synaptic receptors
- treats: anti-cholinesterase overdose
- used in Parkinson’s disease, GIT cramps,
- adverse effects include dry mouth, blurred vision
3
Q
Latrotoxin
A
-increases ach release
4
Q
Botulinum toxin
A
-blocks ach release
5
Q
Vesamicole
A
-inhibits ach storage in vesicles
6
Q
Hemicholinium
A
-blocks ach uptake (stays in the synapse)
7
Q
Benztropine
A
- muscarinic antagonist
- treats Parkinson’s
8
Q
Scopolamine (hyoscine)
A
- muscarinic antagonist
- antiemetic
- treats motion sickness and used in conjunction with anesthesia
9
Q
Ipratropium
A
- muscarinic antagonist
- treats asthma and chronic bronchitis
10
Q
Physostigmine
A
- anti-cholinesterase
- treats Alzheimer’s, atropine poisoning, and glaucoma
11
Q
Echothiophate
A
- anti-cholinesterase
- long acting
- organophosphate
12
Q
Pralidoxime
A
-treatment of organophosphate poisoning
Pharmacology FB2
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