Features of the Galen System
The heart is a pump because
Cardiac myocyte beat spontaneously + maintains pressure
Function of atria
Receive blood from lungs/tissue
The system is ____ but commit to other systems in ____
series, parallel
Arterioles
Muscular walls, regulate local tissue flow
Microcirculation
Exchange between blood and intestinal fluid
Venules + veins
Carry blood back to heart act as a reservoir with 64% of blood
How does size and structure relate to function of vessel walls?
Capillary system ensures
Microcirculation to transport blood into intestinal tissue
In circulation mechanical potential is expressed by
Pressure differences
Cardiac ouput
Amount of blood that leaves the heart/ flows through vessels
Velocity
Amount of blood flowing through per unit of cross sectional area
R =
( density x diameter x velocity )/ viscosity
In laminar flow, particles in blood run _____ to each other for _____
parallel, maximum speed of propagation
Viscocity is a determinant for ______
Velocity
Erthocyte volume decreases with _____ and increases with _____
anaemia, polycythemia
Highest pressure drop in
arterioles
Large arterial pressure tells us
Pressure gradient of whole system
Pm =
(2 x Pdia + Psys) / 3
Ohm’s law in b.p. depends on
Cardiac output and peripheral resistance
Pressure gives an indication of
Mean pressure -> tissue pressure
When arterial pressure higher than systolic pressure
Kurotkoff sounds
When arterial pressure lower than diastolic pressure
Flow becomes continuous
Poiseuille’s Law
Q = K deltaPr-t / (nL) -> sum of blood flow determinants