Class I

Question 1

Class I antiarrhythmics Drugs

Ia-

Answer 1

• Disopyramide
• Procainamide
• Quinidine

Question 2

Class I antiarrhythmic Drugs

Ib-

Answer 2

• Lidocaine (P)

- Mexiletine

Question 3

Class I antiarrhythmic Drugs

Ic-

Answer 3

• Flecainide

- Propafenone

Question 4

Class Ia

MOA-

Answer 4

Decreases depolarization, decreasing automaticity of the ventricular cells; increases ventricular fibrillation threshold

Question 5

Ia

Indications-

Answer 5

management of acute ventricular arrhythmias during cardiac surgery or MI

Question 6

Ia

Contraindications-

Answer 6

• Allergy
• Bradycardia or heart block
• CHF
• Hypotension or shock
• Electrolyte disturbances

Question 7

Ia-

Caution-

Answer 7

• Renal or hepatic dysfunction

- Pregnancy

Question 8

Ia

Adverse Effects-

Answer 8

• CNS: Dizziness, fatigue, slurred speech
• GI: N/V
• CV: Arrhythmias
• Resp. Depression
• Misc: Rash, loss of hair, and potential bone marrow suppression

Question 9

Ia

Drug-Drug

Answer 9

• Quinidine and Digoxin (risk of digoxin toxicity)
• Oral anticoagulants (risk for bleeding)
• Digoxin and Beta-blockers (increased risk for arrhythmias

Question 10

Ia

Drug-Food

Answer 10

• Citrus juice (grapefruit)
• vegetables
• antacids
• milk products

Question 11

Mnemonic

Double Quarter Pounder, with Lettuce, Tomato, and Mayo. More Fries Please.

Answer 11

Disophyramide
Quinidine
Procainamide

Lidocaine
Mexiletine
Tocainide

Moricizine
Flecainide
Propefanone