Clin Path

Question 1

acanthocyte

Answer 1

ripped apart lookin’

- fragmentation, DIC, liver disease

Question 2

echinocytes

Answer 2

spikey

• often artifact when left too long in storage
• ATP depletion
• renal failure or snake bite

Question 3

fragmentation

Answer 3

thermal inury, mechanical, endothelial (vasculitis, hemangiosarc, splenic/hepatic disease)

Question 4

shistocyte

Answer 4

bite taken out

- fragmentation, DIC

Question 5

spherocyte

Answer 5

smaller, perfectly round, no central pallor
- IMHA, Extravascular hemolysis (Mphage)
-

Question 6

ghosts

Answer 6

intravascular hemolysis (immune mediated) causes hemoglobinemia/uria

Question 7

eccentrocytes

Answer 7

oxidative damage, Hb pushed to side, often have heinz bodies(oxidized portion of globin)

Question 8

what measures endogenous GFR

Answer 8

Creatinine (its freely filtered out of blood into glomerulus and NOT REABSORBED in tubules)

INcreased Creatinine when DECreased GFR in chronic renal disease