T cells, thymocytes, NK cells
Adhesion molecule, binding CD58 (LFA-3).
Activate T cells. Responsible for of Sheep’s Red blood cell (SRBC)
CD2
Thymocytes, T cells
Associated with the T cell antigen receptor. Required for cell surface expression of and signal transduction by TCR
CD3
Helper and inflammatory T cells (about two thirds of peripheral T cells, monocytes, macrophages
Co-receptor for MHC class Il molecules. Receptor for HIV1 and HIV2 gp120 . Identifies Th cells also found 8n most treg cells
CD 4
Cytotoxic T cells (about one third of peripheral T cells); Thymocytete subsets
Coreceptor for MHC class l molecules.
Identifies TC cells
CD8
B and T cell precursors, bone marrow stromal cells
Marker for pre BALL
Common Acute Lymphocytic Leukemia
Antigen (CALLA)
CD10
Nk cells, macrophage, neutrophils
Low affinity fc receptor for antibody; mediates phagocytosis and ADCC
CD 16
B cells, follicular dendritic cells
Part of B-cell coreceptor; regulates B-cell development and activation. Forms complex with CD21 (CR2)and CD81 (TAPA-1);
CD19
Receptor for Reed Sternberg cells. Activated by B cells and T cells
CD 30
NK cells subset of T CELLS
Cell adhesion; Isoform of Neural Cell Adhesion Molecule (NCAM)
CD 56
Cell expression: Cortical thymocytes, langerhans cells and dendritic cells, B cells CD1c , intestinal epithelium (CD1d)
Function: MHC class I associated with B2 microglobulin, has special role in antigen presentation
CD1
