CNS Flashcards

(35 cards)

1
Q

Blue man syndrome

A

Amiodarone

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2
Q

Parkinson features and Treatment

A

TRAP features
Syndopa

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3
Q

Progressive supranuclear Palsy

A

Impaired downward gaze
Hummingbird sign

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4
Q

Visual Hallucinations and Dementia

A

Lewy body dementia

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5
Q

Hot cross bun sign

A

MSA-C

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6
Q

Patient on anti Parkinson’s shows pathological gambling which drug is it

A

Pramipexole

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7
Q

Idiopathic Intracranial Hypertension

A

Papilledema 6th CN palsy
T Tetracycline
O Obesity
A Vit A
D Danazol

Rx- Acetazolamide LP

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8
Q

Migraine Management

A

First line NSAIDS
DOC- TRIPTANS
PROPH- Propranolol
5HT1F + LASMIDITAN
CGRP- RimeGIPANT

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9
Q

Viral meningitis

A

WBC Protein increase
Opening pressure Glucose normal

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10
Q

Fungal Meningitis

A

WBC Protein increase
Glucose decreases
Opening pressure Normal
Except in Cryptococcal increases

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11
Q

Charcots Triad

A

Scanning speech
Intention tremors
Nystagmus

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12
Q

Multiple sclerosis

A

Female 30
McDonald’s criteria
Lhermitte sign
Uthoff sign
ON -U/L
Dawson fingers
β interferons

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13
Q

NMO

A

Devics disease
Anti-Aqp4 Ab
Area prostema syndrome
Diencephalon syndrome
Acute myelitis
ON-B/L

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14
Q

Spinothalamic Tracts

A

C/L
Crude touch
Pain
Temperature

Decussation at level of spine

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15
Q

Dorsal column

A

I/L
Fine touch
Proprioception
Vibration

Decussation at level of Medulla
Also in CST

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16
Q

SMA

A

B/L AHC inv
SMN gene
Frog leg position
H/O floppy baby
Ragged doll appearance
Werdnig Hoffman disease, sign
Rx- Zolgensma Nusinersen
Risdiplam. Onasemnogene
(Find sma in words)

17
Q

ALS

A

AHC and CST
Lmn + umn lesion
Bunina bodies
Riluzole Edavarone Neuroprotective
Turusodiol Tofersen

18
Q

Myasthenia gravis

A

NMJ
Thymoma
Sensory, autonomic, DTR, Pupil. N
IOC- Anti-AchR ab level
Anti-musk Ab in ocular MG
Edrophonium test

Repetitive nerve stimulation Decremental response (in LEMS[anti-CA ab] incremental response)
Doc- Pyridostigmine
IVIG. PLEX

19
Q

Stroke localisation

20
Q

West syndrome

A

Infant
Global developmental delay/Regression
Salaam spells
DOC-ACTH
DOC IN TSC- VIGABATRIN

21
Q

Absence seizures

A

Transient LOC
No loss of postural control
3 Hz spike and slow wave
DOC- Ethosuximide
Doc in atypical - Valproate

22
Q

JME

A

Early morning clumsy
3-6 Hz polyspike

Valproate

23
Q

LGS

A

Multifocal sz
<2.5 Hz spike and wave
Valproate
Clobazam

24
Q

Parinaud syndrome

A

Upward gaze palsy
Pineal lesion
Colliers sign- eyelid retraction

25
C/L hemiplegia+ I/L CN 6+7
Millard Gubler Syndrome
26
Midbrain syndrome
C/L Hemiplegia W- Weber 3rd CN palsy B- Benedict + Chorea tremors C- Claude + Hemiataxia Hyperkinesis
27
Valproate s/e and antidote
Hepatotoxic Cyp inhibitor (only inhibitor in antiepileptic drugs) PCOD NTD Antidote- L-carnitine
28
Gum hyperplasia
P phenytoin C cyclosporine V Verapamil
29
Phenytoin
Gum hyperplasia Cyp inducer DRESS syndrome Hirsutism Osteopenia Purple glove Syndrome
30
Carbamazepine S/e
Agranulocytosis Hepatotoxic Teratogenic Carbamazepine SJS Oxcarbamazepine SIADH
31
Brain death
Criteria GCS 3/15 APNEA Test Brainstem reflex absent Signs TC99m HMPAO SPECT White cerebellar sign
32
Osmotic demyelination Syndrome
Rapid overcorrection of Sodium
33
Gaba transaminase inhibitor
Valproate Vigabatrin
34
Chorea Athetosis Hemiballismus
Caudate Gap GP Subthalamic nucleus
35
DBS for Parkinson's
STN>GPi