CNS - ADHD

Question 1

What are the symptoms?

Answer 1

• hyperactivity
• impulsivity
• inattention

Question 2

What is the treatment for children?

Answer 2

• 1st line = methylphenidate (CD2)
• 2nd line = lisdexamphetamine (CD2)
• OR atomoxetine, guanfacine

Question 3

What is the treatment for adults?

Answer 3

• 1st line = methylphenidate/lisdexamphetamine

- OR atomoxetine

Question 4

What are the side effects of methylphenidate?

Answer 4

• appetite loss
• insomnia
• weight loss
• increased heart rate and BP
• tics and tourettes
• growth restriction in kids

Question 5

What would you monitor if a pt was on mehtylphenidate?

Answer 5

• Pulse
• bp
• appetite
• weight
• height
• psychiatric symptoms

Question 6

Which patient groups is methylphenidate contraindicated in?

Answer 6

CVD, hyperthyroidism (characterised by tachycardia), severe hypertension, uncontrolled bipolar disorder, severe depression

Question 7

What are the symptoms of dexamphetamine/lisdexamphetamine overdose?

Answer 7

wakefulness, hyperactivity, paranoia, hallucinations, htn, exhaustion, hypethermia, coma

Question 8

What are the side effects of atomoxetine?

Answer 8

• suicidal ideation (esp at the start of treatment and after dose change)
• hepatotoxicity
• qt prolongation
• constipation
• tachycardia
• increased bp

Question 9

What do you monitor with atomoxetine?

Answer 9

Pulse, BP, Appetite, Weight and height, Psychiatric symptoms