APEX > Coag > Flashcards

Coag Flashcards

(13 cards)

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1
Q
A

Factor deficiency or anticoagulation

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2
Q
A

Impaired platelet number or function

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3
Q
A

Primary fibrinolysis

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4
Q
A

Hypercoagulation

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5
Q
A

Stage 1 DIC: hypercoaguable state with secondary fibrinolysis

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6
Q
A

DIC stage 2: hypocoaguable

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7
Q

Platelet adhesion is a/w?

A

vWF

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8
Q

Platelet activation and aggregation is a/w?

A

ADP & thromboxane A2

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9
Q

Final common pathway

A

10, 5, 2, 1
(Think dollar denominations $10, $5, $2, $1)

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10
Q

What is the mnemonic for the coagulation factors?

A
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11
Q
A
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12
Q

Which pathway is faster?

A

Extrinsic (15 sec) vs intrinsic (6 min)

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13
Q

What 2 mechanisms turn off fibrinolysis?

A
  1. tPA inhibitor inhibits the conversion of plasminogen to plasmin
  2. Alpha-2 antiplasmin inhibits the action of plasmin on fibrin
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