What happens in high altitude?
pO2 decreases
cerebral vessels dilate
increase ICP
Herniation can occur
Factors that lead to increased flow
CNS: increased pCO2; decreased pO2 Lungs; increased pO2 Muscles: increased pCO2; decreased pH CV: adenosine Skin: increased temp; increased pCO2 GI: food, esp fats Renal: increased PGE2; dopamine; ANP
Direct Coombs test
detects antibodies DIRECTLY on the surface of RBC
used to detect Warm (IgG) and
Cold (IgM) agglutinin dz
OR
used to screen babies for hemolytic dz of the newborn
positive nitrogen balance
amino acid (AA) intake > excretion
examples:
growth
pregnancy
Indirect Coombs test
detect antibodies IN the plasma
used to screen for antibodies in blood transfusion
used to screen mom in hemolytic dz of new born