Complement System- Alternative

Question 1

What pathway can be activated by membrane-bound C3b generated from lectin pathway or classical pathway?

Answer 1

Alternative

Question 2

Why is the alternative pathway an amplifier for the lectin and classical pathway?

Answer 2

Both L and C generate C3b

Question 3

Alternative pathway can be activated by?

Answer 3

Spontaneous hydrolysis of C3

Question 4

What factor binds to the pathogen surface during C3 convertase in the alternative pathway?

Answer 4

Factor D

Question 5

What are destroyed as fast as they are generated in healthy animals?

Answer 5

C3b

Question 6

What stabilizes C3 convertase complex on the pathogen surface?

Answer 6

Properdin (factor P)