Compounding I: Basics

Question 1

Non-sterile compounding follows which standards for compounding preparations?

Answer 1

USP 795

Question 2

Sterile compounding follows which standards for compounding preparations?

Answer 2

USP 797

Question 3

Handling hazardous drugs follows which standards for compounding preparations?

Answer 3

USP 800

Question 4

Non-sterile compounding is used to:

Answer 4

1. Prepare a dose or formulation that is not commercially available
2. Avoid an excipient
3. Add flavor

Question 5

Non-sterile are administered via:

Answer 5

PO
via tube
rectally 
vaginally
topically
nasally
otic

Question 6

Sterile compounding is used to prepare:

Answer 6

1. IV drugs
2. IM and SC drugs
3. Ear drops
4. Irrigations
5. Pulmonary inhalations

Question 7

ISO set standards for:

Answer 7

air quality (size of particle per volume)

**the lower the particle count the cleaner the air

Question 8

Buffer area must be at least an ISO

Answer 8

ISO 7

Question 9

Anteroom (hand-washing and garbing) must be at least an ISO

Answer 9

ISO 8 if it opens into a positive-pressure buffer area (non-HD sterile compounding)

ISO 7 if it opens into a negative-pressure buffer area (HD sterile compounding)

Question 10

How often does a HEPA filter be recertified by a specialist?

Answer 10

6 months or anytime a PEC has been moved

Question 11

The primary engineering control (PEC, called the sterile hood, or isolator, if using a glove box) is an ISO of what?

Answer 11

ISO 5