COMT & SERT

Question 1

What does the COMT gene do

Answer 1

It reduces dopamine action

Question 2

What happens if there is a variation in the amount of COMT gene

Answer 2

Dopamine can’t be controlled in the synapse, and therefore accumulates

Question 3

What does the SERT gene do

Answer 3

It affects the transport of serotonin, decreasing its levels

Question 4

What happens when the SERT gene is faulty

Answer 4

Too much serotonin is reabsorbed during synaptic transmission

Question 5

What happens when too much serotonin is reabsorbed

Answer 5

Lower kevels of serotonin transport to the next neuron