USMLE > Concise TB Drugs > Flashcards

Concise TB Drugs Flashcards

(8 cards)

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1
Q

Rifampin MOA

A

Inhibition of bacterial DNA-dependent RNA polymerase

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2
Q

Rifampin side effects

A

Red-orange body fluids
Rash
Cytopenia
GI issues

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3
Q

Isoniazid MOA

A

Inhibition of mycolic acid synthesis

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4
Q

Isoniazid side effects

A

Neurotoxicity

Hepatotoxicity

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5
Q

Pyrazinamide MOA

A

Unclear

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6
Q

Pyrazinamide side effects

A

Hepatotoxicity

Hyperuricemia

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7
Q

Ethambutol MOA

A

Inhibition of arabinosyl transferase

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8
Q

Ethambutol side effects

A

Optic neuropathy

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