Controlling enzyme Function

Question 1

3 ways to control enzyme functions

Answer 1

Competitive inhibitors, allosteric regulators, feedback inhibition

Question 1

Controlling enzyme functions

Answer 1

Allows a control over the formation of various unwanted products

Question 2

Competitive inhibitors

Answer 2

• Molecules that mimic (copy) substrate molecules and end up blocking the normal substrate so there is “competition” for the active site.
  *This can slow down or sometimes stop enzyme functions

Question 3

Is this a natural occurence?

Answer 3

It can be an natural occurence (where your body purposely slows down enzyme) BUT it can also happen because of toxins that enter the cells

Question 4

Allosteric regulators

Answer 4

Molecules that bind to all the allosteric site of an enzyme

Question 5

What are the two types if allosteric regulators?

Answer 5

Noncompetitive inhibitors and allosteric activators

Question 6

Noncompetitive inhibitors

Answer 6

Inhibits the enzymes from functioning by having a non-substrate molecule attach to an allosteric site (not the active site) so that the enzyme no longer functions

Question 7

Example of a noncompetitive inhibitor

Answer 7

pesticide DDT

Question 8

Allosteric activators

Answer 8

• Molecules that bind to allosteric sites of enzymes and they can alter the protein conformation
• Inactive enzymes become “activated” and the new active site becomes more stabilized.

Question 9

Feedback inhibition

Answer 9

• The process by which an enzyme is inhibited by a product that has formed after a series of other enzymatic reactions
• Self regulating
• Final product can act like an allosteric inhibitor

Question 10

Note about feedback inhibiton

Answer 10

This is a good way of regulating the production of molecules so that you don’t unnecessarily make too much of a product within a cell

Question 11

Example of feedback inhibition

Answer 11

ATP allosterically inhibits more making of itself