CSF

Question 1

where is CSF produced

Answer 1

choroid plexus

Question 2

how much CSF is produced per hour in an adult

a. 10 mL
b. 15 mL
c. 20 mL
d. 25 mL

Answer 2

20 mL

Question 3

T or F. CSF resembles the plasma ultrafiltrate

Answer 3

false

Question 4

CSF

tube 1 is for:

Answer 4

chemistry and serology

Question 5

CSF

tube 2 is for:

Answer 5

microbiology

Question 6

CSF

tube 3 is for:

Answer 6

CM/hematology/cell counting

Question 7

CSF

tube 4 is for:

Answer 7

additional chemistry/serology/microbiology

Question 8

if testing will be delayed:

tube 1 should be stored at:

Answer 8

frozen temp

Question 9

if testing will be delayed:

tube 2 should be stored at:

Answer 9

room temp

Question 10

if testing will be delayed:

tube 3 should be stored at:

Answer 10

refrigerated temp

Question 11

if only 1 CSF tube can be collected, what test should be prioritized?

Answer 11

microbiology

Question 12

CSF appearance:

hazy, turbid, milky

Answer 12

microbes, protein

Question 13

CSF appearance:

oily

Answer 13

radiographic contrast media

Question 14

CSF appearance:

bloody

Answer 14

traumatic tap, rbcs

Question 15

CSF appearance:

xanthochromic

Answer 15

hemorrhage, bilirubin, hemoglobin, carotene

Question 16

CSF appearance:

clotted

Answer 16

BBB disorders, fibrinogen

Question 17

CSF appearance:

pellicle

Answer 17

BBB disorders, tubercle meningitis, clotting factors

Question 18

differentiate intracranial hemorrhage vs traumatic tap

Answer 18

traumatic tap - uneven blood distribution, has clot, not xanthochromic

Question 19

when is the time RBC count is done in CSF?

Answer 19

to correct WBC count because of traumatic tap

Question 20

T or F. CSF should be diluted first whether it is turbid or clear

Answer 20

False. if the sample is clear, no need for dilution

Question 21

counting area for WBC count

Answer 21

4 WBC squares

Question 22

CSF WBC proportion in adults

Answer 22

lymph 30

mono 70

Question 23

CSF WBC proportion in children

Answer 23

lymph 70

mono 30

Question 24

term for increased mononuclear count

Answer 24

pleocytosis

Question 25

condition associated with pleocytosis with increased neutrophils

Answer 25

bacterial meningitis

Question 26

condition associated with moderate pleocytosis with increased mononuclears

Answer 26

viral, tubercular, fungal, or parasitic meningitis

Question 27

what type of WBC is seen in CSF if the patient has infection from Coccidioides immitis?

Answer 27

eosinophil

Question 28

this WBC indicates previous hemorrhage

Answer 28

macrophage

Question 29

these are degraded phagocytosed RBCs; stains dark-blue or black granules

Answer 29

hemosiderin granules

Question 30

further degradation product, iron free

Answer 30

hematoidin crystals

Question 31

cells that are seen in the epithelial lining of choroid plexus, no nucleoli

Answer 31

choroidal cells

Question 32

seen in the lining of ventricles and neural canal, seen in clusters

Answer 32

ependymal cells

Question 33

seen in the lining cells of arachnoid, also seen in systemic malignancies

Answer 33

spindle-shaped cells

Question 34

these cells indicate dissemination from lymphoid tissues due to complication of acute leukemia

Answer 34

lymphoma cells

Question 35

most frequently performed chemical test for the differentiation of meningitis

Answer 35

CSF protein

Question 36

when CSF protein is higher than glucose, what kind of meningitis is present?

Answer 36

bacterial

Question 37

CSF protein NV a. 35-55 b. 30-50 c. 15-45 d. 5-15

Answer 37

15-45

Question 38

most abundant protein in CSF

Answer 38

albumin

Question 39

second most abundant protein in CSF

Answer 39

prealbumin

Question 40

two methods of CSF protein measurement

Answer 40

- nephelometry | - dye-binding

Question 41

protein that is solely found in CSF

Answer 41

tau transferrin

Question 42

to determine whether IgG production is within CNS or due to damaged blood-brain barrier

Answer 42

IgG index

Question 43

indicates recent destruction of myelin | sheath (demyelination)

Answer 43

myelin basic protein