What are the 3 counselling points of Dipyridamole?
- Take 30-60 mins before food
- Special container: Keep capsules in this
- 6 week expiry date
What is stage 1 hypertension?
- Clinical BP less than 140/90
- Less than 135/85 hbpm
- Only treat if target organ damage or other health conditions or CVD risk over 20%
What is stage 2 hypertension?
- 160/100
- Treat all cases
What is stage 3 hypertension?
- Over 180 or 100
- Emergence
What is the BP target for patients under 80?
- 140/90
- 130/80 if other risks
What is BP target for patients over 80?
-150/90
What is BP target in renal disease?
- 140/90
- 130/80 if CKD or also diabetes or proteinuria
What is the BP target in diabetes?
- 140/90
- 130/80 if complications
What is the BP target in pregnancy?
- 150/100 if chronic
- 140/90 if target organ damage or after birth
Which Beta blockers have ISA? What is the significance of this
- Pindolol
- Acebutolol
- Celiprolol
- Oxprenolol
- Significance is they cause less bradycardia and coldness of extremities
Which Beta blockers are water soluble? What is the significance of this
- Celiprolol
- Atenolol
- Nadolol
- Sotalol
- Significance is they cause less nightmares and dose needs reduced in renal impairment
Which Beta blockers are cardio-selective? What is the significance of this
- Bisoprolol
- Atenolol
- Metoprolol
- Nebivolol
- Acebutolol
- Significance is they have lesser side effects on airways
Which Beta blockers are given once daily?
- Bisoprolol
- Atenolol
- Celiprolol
- Nadolol
Which drug class interacts with beta blockers to cause hyperglycaemia?
-Thiazide-like diuretics
At what eGFR are thiazides ineffective?
-Less than 30
What is step 1 of heart failure treatment?
- ACEI plus Beta blocker
- Loop diuretic if fluid overload
What is step 2 of heart failure treatment?
- Spironolactone or eplerenone
- Entresto if LVEF less than 35%
What is step 3 of heart failure treatment?
- Ivabradine or digoxin
- Hydralazine and isosorbide are alternative given by specialist
What are target cholesterol levels?
- 5 or less for total
- 3 or less for LDL
- 1 or more for HDL
- Less than 1.7 for triglycerides
What must be corrected before initiating statin treatment?
-Hypothyroidism
What statins are considered high intensity? (>40% LDL reduction)
- Atorvastatin 20-80mg
- Rosuvastatin 10-40mg
- Simvastatin 80mg
-Simvastatin 20mg is the max dose with what drugs?
- Amiodarone
- Amlodipine
- Verapamil or diltiazem
Simvastatin 10mg is the max dose with what drugs?
-Fibrates
Atorvastatin 10mg is max dose with which drug?
-Ciclosporin
