Deck D

Question 1

Two reasons why many synthetic ad herbal drugs posses the problem of poor bioavailability.

Answer 1

Very low water solubility

Poor permeation through the biological membrane

Question 2

Why is it difficult for most bioactive molecules of plants to pass through the lipid-rich biological membrane and be absorbed by humans?

Answer 2

Large molecular weight

Low lipid solubility

Question 3

Liposomes vs. Phystosomes (4)

Answer 3

1. Liposomes»_space; Phytosomes
2. Phytosomes form new bonds
3. Liposomes have 100s-1000s of PC molecules vs. 1:1 or 2:1 for phytosomes
4. Liposomes surround ingredients while phytosomes anchor them to the polar head of the phospholid by chemical bonding.