Definitions

Question 1

SIRS

Answer 1

Exaggerated/dysregulated defense response to an acute stressor

RR >20, paCO2 <32
HR >90
WCC >12, WCC<4
T >38, T<36

Question 2

Sepsis

Answer 2

SIRS with a foci of infection

Question 3

Septic shock

Answer 3

Sepsis with ongoing haemodynamic instability despite resuscitation

Question 4

Barrett’s definition and classification

Answer 4

Two components -
Endoscopic evidence of salmon pink columnar epithelium extending above GOJ
Biopsies showing intestinal metaplasia, with presence of goblet cells

Short <3cm
Long equal to or >3cm

Question 5

Cancers associated with Li Fraumeni

Answer 5

Sarcoma
Breast
Leukaemia
Adrénal