Depression

Question 1

what is the risk of completed suicide for depression?

Answer 1

10% risk of completed suicide

Question 2

what is the the lifetime risk of depression?

Answer 2

16-17% lifetime risk

Question 3

What is the criteria for a major depressive episode?

Answer 3

within 2 weeks at least 5 of:

MUST HAVE dysthymia and anhedonia

“SADAFACES”

• S - sleep disturbance
• A - appetitie/weigth change
• D - dysthymia for most of the day
• A - anhedonia
• F - fatigue
• A - agitation (psychomotor)
• C - concentration difficulty/indecisiveness
• E - excessive guilt/hopelessness
• S - suicidal ideation/attempts/plans

Question 4

what are the risk factors for completed suicide in depression?

Answer 4

• being an older man
• previous suicide attempt
• alcohol
• loss of job
• relationship breakdown

Question 5

how effective is the first line treatment of major depressive disorder?

Answer 5

60% improve, also 30% on placebo improve

Question 6

What are some organic causes of depression?

Answer 6

• hypothyroidism
• anaemia (Fe, B12, flate, alcoholism)
• hypercalcaeia
• syphilis
• hyponatraemia
• dementia
• cancer

Question 7

what is the first line treatment of depression?

Answer 7

SSRIs

• sertraline 5 - 15mg
• escitalopram 10-20 mg

Question 8

What are the features of melancholic depression?

Answer 8

“MELANcholic”

• Morning worsening of symptoms, psychoMotor agitation/retardation, early Morning wakening
• Excessive guilt
• Loss of emotional reactivity
• ANorexic
• ANhedonia