Derm Epidemiology

Question 1

Seborrheic keratosis

Answer 1

M>F
AD inheritance
sudden appearance associated w/ malignancy, commonly gastric adenocarcinoma

Question 2

Rosacea

Answer 2

F>M

highest prevalence in fair-skinned people

Question 3

Atopic dermatitis

Answer 3

• almost 15% of children in developed countries under age 5 are affected
• associated with personal or family hx of atopy (asthma, hay fever), anaphylaxis, eosinophilia
• Polygenic inheritance: one parent >60% chance for child; 2 parents >80% chance

Question 4

Seborrheic dermatitis

Answer 4

• common in infants and adolescents
• more severe in immunocompromised pts
• in adults, can cause dandruff (pityriasis sicca)

Question 5

lichen planus

Answer 5

• 1%

- 30-60 yo, F>M

Question 6

Psoriasis

Answer 6

risk factors: smocking, obesity, alcohol, drugs, infections

Question 7

Bullous Pemphigoid

Answer 7

mean age of onset: 60-80 yo, F=M

Question 8

*pemphigus vulgaris

Immunofluorescence show IgG and C3 deposition intraepidermally
circulating serum anti-desmoglein IgG antibodies

Answer 8

• 40-60 yo
• higher prevalence in Jewish, Mediterranean, asians
• Paraneoplastic pemphigus may be associated with thymoma, myasthenia gravis, malignancy, and use of D-pencillamine

Question 9

Exanthematous drug reaction

Answer 9

common causative agents: Penicillin, Sulfonamides, phenytoin

Question 10

Drug induced hypersensitivity syndrome (DIHS)/ drug reaction with eosinophilia and systemic symptoms (DRESS)

Answer 10

common causative agents: anticonvulsants (phenytoin, phenobarbital, carbamazepine, lamotrigine), sulfonamides, allopurinlo

Question 11

Urticaria

Answer 11

second most common cutaneous drug rxn

common causative agents: penicillins, ACEI, analgesics/anti-inflammatoy, radiographic contrast media

Question 12

Serum sickness-like rxn

Answer 12

more prevalent in kids 0.02-0.2%
common causative agents:
cefaclor in kids,
bupropion in adults