epigastric pain + jaundice + courvoiseir sign + hi conjugate Bili in longterm smoker: DX, Test,
Cholangiocarcinoma
pancreatic cancer
CT scan
CA-99/CEA markers
NBS to relief severe pain and jaundice in unresectable cholangiocarcinoma/pancreatic cancer
ERCP
Rapid onset hirsutism
Hi androgen + virilization+US with ovarian cyst
PCOS
Rapid onset hirsutism
Hi androgen + virilization+ hi 17 hydoxyprogesteron
nonclassic CAH
Rapid onset hirsutism
Hi androgen + virilization+ galactorrhea/ amenorrhea
prolactinoma
Rapid onset hirsutism
Hi androgen + virilization+ moon face, buffalo hump
cushing
dexa not suppress/ hi 24 hr urine cortisol
Rapid onset hirsutism
Hi androgen + virilization+hat/ shoes does not fit
acromegaly
delirium
acute, fluctuating attetion, distrubance in thinking and conciousness
Delirium + fever, crackle, leukocytosis
NBS
UTI and Pneumonia
CRX, UA, CBC, CMP, medication review
risk factor
pleural effusion
smoking–> malignacy
NBS pleural effusion sign
low breath sound, friction rub, dull to percussion
X-ray
thoracetesis
low protein
characteristics of Nephrotic syndrome
massive edema(periorbitl, ascites, anasarca)
frotty/foamy urine
weight gain
no RBC cast
Oval fat bodies- multase cross
normal complement except Lupus
pt with low albumin, edema, hi lipid sudden flank pain
Renal vein thrombosis
dt hypercoagulability
pt with low albumin, edema, hi lipid, fatty cast always sick, why
low IgG
dt loss of protein
why is vit D and Ca low in nephrotic syndrom
Kidney function
loss of carrier protein
nephrotic
HIV , heroin, obese pt with proteinuria
FSGS
nephrotic
Kid +viral infection , low almumin
minimal change
nephrotic
autoimmune, maligancy thick GBM, spike ad dome
membranous nephropathy
nephrotic
kimmelsteal wilson
Diabetic (>10y)
nephrotic
Chronic inflammation +Nephrotic
lab
AL or AA amyloid
congo red/ apple green
RBC cast, HTN, Azotemia, Hematuria, oliguria
Nephretic
Dark urine + HTN, protein<3.5
Nephritic
sequence of neoplasm progression
AK53
APC
KRAS
P53
Peutz-jeghers association
Pacreatic cancer
pigmented lips