Define bipolar disorder
Recurrent episodes of depression + mania (or hypomania)
Features of depressive episodes (in bipolar)
Can be severe
Define features of manic episodes in bipolar
Excessively elevated mood + energy - significantly impacting their normal functions
(e.g. caring and work responsibilities)
What are hypomanic episodes in bipolar?
Milder symptoms of mania - without having a significant impact on their function
Features of mania
What are mixed episodes in bipolar?
Mix of symptoms or rapid cycling between mania and depression
Which criteria is a diagnosis of bipolar disorder made from?
Diagnostic and Statistical Manual of Mental Disorders (DSM-5)
Define Bipolar I disorder
Bipolar I disorder = at least one episode of mania
Define Bipolar II disorder
Bipolar II disorder = involves at least one episode of major depression + at least one episode of hypomania
Bipolar I = at least one episode of mania
Bipolar II = at least one major depression + mania episode each
Define cyclothymia
Cyclothymia = milder symptoms of hypomania + low mood
The symptoms = not severe enough to significantly impair their function
Define unipolar depression
Unipolar depression = when the person only has episodes of depression - without hypomania or mania
Management for an acute manic episode (bipolar disorder)
Bipolar disorder - think OLANZAPINE!
Management for an acute depressive episodes (bipolar disorder)
Long-term management for bipolar disorder
Lithium
Serum lithium levels (taken 12 hours after the most recent dose).
Target range = 0.6-0.8 mmol/L
If too high → lithium toxicity
Long term = Lithium
Name some side effects of lithium
What are the alternatives to lithium for long-term management of bipolar disorder?
Sodium valoproate + olanzapine
A 30 year old woman has recently diagnosed with bipolar II disorder. What drug cannot be prescribed to her?
Sodium valproate
(Teratogenic → neural tube defects + developmental delay)
What plans can family members put in place for individuals with bipolar disorder?
Define obsessions
Obsessions = unwanted + uncontrolled thoughts and intrusive images
E.g. overwhelming fear of contamination with dirt or germs or violent or explicit images that keep appearing in their mind
Define compulsions
Compulsions = repititive actions the personal feels they must do - generating anxiety if not done.
Often these compulsions are a way to handle their obsessions
The OCD cycle
What are the criterias used in diagnosing OCD?
The Yale-Brown Obsessive Compulsive Scale (Y-BCOS) = can be used to assess the severity of symptoms
Management of OCD
Mild OCD: Education + self-help
Significant OCD:
* Cognitive behavioural therapy (CBT) + exposure and response prevention (ERP)
* SSRIs
* Clomipramine (a tricyclic antidepressant)
Exposure and response prevention = involves gradually facing the obsessive thoughts and anxiety without completing the compulsions.
PTSD can result from any event that the individual finds traumatic. Examples include….