Diuretics

Question 1

What are the 5 groups of diuretics?

Answer 1

Osmotic
Carbonic anhydrase inhibitors
Loop
Thiazides 
K sparing

Question 2

What are diuretics?

Answer 2

Drugs that increase urine output

Question 3

What are the 3 main indications that diuretics are needed?

Answer 3

oedema (swelling)
congestive heart failure
hypertension

Question 4

Give an example of an osmostic diuretic

Answer 4

Mannitol

Question 5

How do osmotic diuretics work?

Answer 5

Inhibit water reabsorption in PCT, increases urine output

Question 6

Give an example of a carbonic anhydrase inhibitor?

Answer 6

Acetazolamide

Question 7

What is the mechanism of CA inhibitors?

Answer 7

suppress H+ production
reduce NA/H exchange
less Na+ reabsorption
produces alkaline urine