1
Q
Carbonic anhydrase inhibitors
A
- acetazolamide
- methazolamide
- dichlorophenamine
2
Q
carbonic anhydrase inhibitors MOA
A
- inhibits Ca which inhibits H+ secretion in the PCT
- bicarb and Na are blocked from reabsorption
- hypokalemic metabolic acidosis
3
Q
osmotic diuretics
A
- mannitol
- urea
4
Q
osmotic diuretics MOA
A
- increase osmotic gradient in the PCT
- decreased Na reabsorption = water follows
- risk of hypernatremia
5
Q
what ions are excreted with mannitol
A
- water
- Na
- Cl-
- HCO3
6
Q
where does fluid move when mannitol is administered
A
- draws fluid from intracellular to extracellular spaces
- acutely expands intravascular volume
