helicase
unwinds DNA helix at replication fork
DNA polymerase III
synthesizes new DNA strand by adding nucleotides to an RNA primer
single stranded binding protein
binds & stabilizes single-stranded DNA until it’s used as a template
topoisomerase
relaxes supercoiled DNA ahead of the replication fork so that replication may proceed
primase
begins synthesis of RNA primer
DNA polymerase I
degrades RNA primer by replacing the strand
DNA ligase
joins (ligates) Okazaki fragments into daughter strands