FOM Summative > DNA Replication > Flashcards

DNA Replication Flashcards

(8 cards)

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1
Q

Steps of DNA Replication

A
  1. Identify Origins of replication
  2. unwind
  3. prime and elongate
  4. ligate
  5. assemble to chromatin
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2
Q

ORC

A

Origin of Replication Complex. Binds to DNA in late M1 early G1

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3
Q

Cdt1/Cdt6 and MCM

A

licensing factors. MCM is helicase and unwinds DNA

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4
Q

Primase

A

RNA/DNA alpha. primes DNA

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5
Q

DNA Polymerase

A

DNA pol DELTA clamps on

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6
Q

Topoisomerase

A

prevents overwinding

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7
Q

How does DNA repair phosphodiester nick in Okazaki Fragments

A

dna ligase + ATP

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8
Q

Telomerase

A

Reverse Transcriptase

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