Drug- CM Interactions

Question 1

Variability of interactions of herbal product because….

Answer 1

1. Constituent variability
2. Changing brands or batches = unpredictable outcomes
3. Formulation used …
   Garlic and allicin content (vary)
4. Dose and timing of use
5. Route
6. Patient group… elderly, infant, pregnant

Question 2

Which metabolic enzymes are most important

Answer 2

CUP1A2, 2D6, 3A4

Question 3

CM INTERACTIONS WITH COVID19 ANTIVIRALS

Answer 3

1. St john’s wart
2. Zinc
3. Marshmallow root (A. Officinalis).

=avoid or take antivirals 2 hours before or 6 hours after the CM

Question 4

Medicines that interact with cannabis

Answer 4

Baclofen, lithium, clobazam, TCA, opioids