Ebola

Question 1

What is the family, genus, and species of the current Ebola outbreak?

Answer 1

Flioviridae, Ebola, Zaire

Question 2

What kind of virus is Ebola?

Answer 2

enveloped, (-) strand RNA virus

Question 3

Where does Ebola replicate?

Answer 3

in the cytoplasm

Question 4

Eboa virions are _____ with multiple genomes strung together (_____ shape).

Answer 4

polyploid; filamentous

Question 5

What is the purpose of the Ebola glycoprotein?

Answer 5

it’s part of the viral envelope- helps attachment/entry and pathogenicity

Question 6

Name 2 important Ebola matrix proteins and what they do.

Answer 6

1. VP40 main part of the virion, important for structure, stability, assembly, budding
2. VP24: assembly, budding, nucleocapsid assembly, immune defense

Question 7

What forms the nucleocapsid and nucleoprotein in Ebola?

Answer 7

VP30 and nucleoproteins

Question 8

What do VP35 and L do in Ebola?

Answer 8

they’re the RNA-dependent-RNA-pol

Question 9

Ebola _____ are polyploid with _____ strung together (filamentous shape).

Answer 9

virions; multiple genomes

Question 10

How does Ebola enter the body? Where does it infect first?

Answer 10

through mucosa or cuts in the skin; phagocytic cells