Elderly

Question 1

Which drugs are the elderly more sensitive too?

Answer 1

Opioids, benzos, anti psychotics, parkinson’s drugs

Question 2

What is the most important effect of ageing on prescribing?

Answer 2

Reduced renal clearance

Therefore excrete drugs slowly and more susceptible to nephrotoxics

Question 3

How might adverse reactions present in the elderly?

Answer 3

Confusion, constipation, hypotension, falls

Question 4

Why should benzodiazepines be avoided?

Answer 4

Can cause falls

Question 5

When should diuretics be avoided?

Answer 5

Long term for gravitational oedema

Question 6

Which analgesia is dangerous in the elderly?

Answer 6

NSAIDs are more dangerous: bleeding, cardiac and renal implications
Use paracetamol, if needed use low dose ibuprofen then opioid
Use PPI prophylaxis